Мultiple myeloma incidence rates in the Republic of Belarus

Abstract

Мultiple myeloma is one of the most expected malignant neoplasms, which could be associated with radiation impact. Thus the aim of this study was to estimate multiple myeloma rates in Belarus within 1991-2014. Data of Belorussian Cancer Registry were analyzed by calculating crude rates (CR), age-specific rates (AsR) and age standardized rates (ASR). Trend analysis was realized by investigating average annual percentage change (APC). In analyzing AsR the risk of the disease in the first 30 years of life is minimum. After 35 years the risk is dramatically growing. After 75 years the risk of multiple myeloma starts decreasing. Dynamic parameters have grown in both crude and standardized incidence rates (APC is about 3.5%). CR is higher in males than females as opposed to ASR. CR and ASR are higher for urban rather than rural residents. The data obtained can be used in further epidemiological studies of multiple myeloma risk in the groups of high radiation exposure.