Effect of ascorbic acid on wound process during implantation of «Esfil» and «ProGrip» in the experiment
Abstract
One of the problems of modern surgery is treatment of ventral hernias. It is important to study the process of wound healing in the area of implantation of prosthesis depending on the drugs use that improve the processes of regeneration and repair, in particular ascorbic acid. We carried out the experimental study of 200 white mice with the implanted prosthesis Esfil and ProGrip whose diet included ascorbic acid. The inflammatory response was less pronounced after using ascorbic acid and reached its minimum with endoprosthesis material ProGrip. There was significantly higher content of fibroblasts in the connective tissue capsule after the combined use of the endoprosthesis ProGrip and ascorbic acid.
About the Authors
V. A. Lazarenko
Kursk State Medical University
Russian Federation
Russian Federation
S. V. Ivanov
Kursk State Medical University
Russian Federation
Russian Federation
I. S. Ivanov
Kursk State Medical University
Russian Federation
Russian Federation
A. V. Tsukanov
Kursk State Medical University
Russian Federation
Russian Federation
A. V. Golikov
Kursk State Medical University
Russian Federation
Russian Federation
I. A. Ivanova
Kursk State Medical University
Russian Federation
Russian Federation
D. V. Tarabrin
Kursk State Medical University
Russian Federation
Russian Federation
G. N. Gafarov
Kursk State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Lazarenko V.A., Ivanov S.V., Ivanov I.S., Tsukanov A.V., Golikov A.V., Ivanova I.A., Tarabrin D.V., Gafarov G.N. Effect of ascorbic acid on wound process during implantation of «Esfil» and «ProGrip» in the experiment. Kursk Scientific and Practical Bulletin "Man and His Health". 2015;(4):93-96. (In Russ.)
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