Interstitial fibrosis as a determining factor in typing left ventricular myocardial remodeling in elderly patients with arterial hypertension
Abstract
In order to establish the severity of interstitial myocardial fibrosis in different types of geometric left ventricular remodeling during aging we examined 100 elderly patients with II-III stage arterial hypertension (AH) by electro- and echocardiography with calculation of the index of interstitial collagen volume fraction. It was found that the progression of the interstitial fibrosis severity is accompanied by reducing a number of patients with the regular geometry of the left ventricle (LV) myocardium and its isolated form and a substantial increase in concentric types of remodeling. Typing LV geometry and evaluation of myocardial fibrosis intensity of its extracellular matrix against the background of arterial hypertension in aging are necessary for the development of individual corrective measures to improve the functioning, quality of life and prognosis.
About the Authors
N. K. Gorshunova
Kursk State Medical University, Kursk
Russian Federation
Russian Federation
N. V. Medvedev
Kursk State Medical University, Kursk
Russian Federation
Russian Federation
V. V. Savich
Kursk State Medical University, Kursk
Russian Federation
Russian Federation
O. L. Usenkova
Kursk State Medical University, Kursk
Russian Federation
Russian Federation
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Review
For citations:
Gorshunova N.K., Medvedev N.V., Savich V.V., Usenkova O.L. Interstitial fibrosis as a determining factor in typing left ventricular myocardial remodeling in elderly patients with arterial hypertension. Kursk Scientific and Practical Bulletin "Man and His Health". 2015;(3):11-15. (In Russ.)
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