Preview

Humans and their health

Advanced search

Influence of omega-3 unsaturated fatty acids on indices of diastolic left ventricular function in patients with acute coronary syndrome with outcome to acute myocardial infarction

https://doi.org/10.21626/vestnik/2017-4/09

Abstract

We conducted an open, randomized study of 100 patients divided into two equal groups with the diagnosis of acute coronary syndrome with an outcome to unstable angina in 41% of cases, and 59% to acute myocardial infarction, in which the main indices of diastolic function of the left ventricle were evaluated. Patients of the main group (n = 50) included in the study were administered Omakor (1 g / day) in addition to the complex therapy from the first hospital day during 2 weeks. To assess the morphofunctional parameters of the myocardium, patients underwent ultrasound examination of the heart on the days 1 and 14 of the therapy. It was shown that Omakor in the complex therapy accelerates the restoration of diastolic function of the myocardium, which is manifested in patients with acute coronary syndrome by a decrease in IVRT and DTE; in patients with acute myocardial infarction - a decrease in IVRT.

About the Authors

V. P. Mikhin
Kursk State Medical Universit
Russian Federation


A. I. Shveinov
Kursk City Clinical Emergency Hospital
Russian Federation


A. V. Kharchenko
Kursk State Medical Universit
Russian Federation


D. A. Vasilyeva
Kursk State Medical Universit
Russian Federation


G. V. Panchenko
Kursk City Clinical Emergency Hospital
Russian Federation


N. I. Gromnatsky
Kursk State Medical Universit
Russian Federation


N. G. Stepanets
Kursk City Clinical Emergency Hospital
Russian Federation


References

1. Говорин А.В., Филев А.П. Омега-3 полиненасыщенные жирные кислоты в лечении больных с сердечно-сосудистыми заболеваниями // Рациональная Фармакотерапия в Кардиологии. - 2012. - № 8 (1). - С. 95-102.

2. Карпов Ю.А. ω-3-полиненасыщенные жирные кислоты: применение сегодня и перспективы использования в клинической практике // Атмосфера. Новости кардиологии. - 2014. - № 2. - С. 43-50.

3. Михин В.П., Швейнов А.И., Харченко А.В., Чернятина М.А., Антопольская Е.В., Панченко Г.В. Состояние параметров свертывающей системы крови у больных с острым коронарным синдромом на фоне приема Омакора в период госпитальной реабилитации // Врач-аспирант. - 2017. - Т. 82, № 3. - С. 35-39.

4. Перепеч Н.Б. Острый коронарный синдром: патогенез, диагностика, лечение, реабилитация (часть 1) // Кардиосоматика. - 2016. - № 1. - С. 70-81.

5. Fareed J. Antithrombotic therapy in 2014: Making headway in anticoagulant and antiplatelet therapy / J. Fareed // Nat. Rev. Cardiol. - 2015. - Vol. 12, N 2. - P. 70-71. - doi: 10.1038/nrcardio.2014.222.

6. Piepoli M.F., Hoes A.W., Agewall S., Albus C., Brotons C., Catapano A.L., Cooney M.T., Corrà U., Cosyns B., Deaton C., Graham I., Hall M.S., Hobbs F.D., Løchen M.L., Löllgen H., Marques-Vidal P., Perk J., Prescott E., Redon J., Richter D.J., Sattar N., Smulders Y., Tiberi M., van der Worp H.B., van Dis I., Verschuren W.M., Authors/Task Force Members. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR) // Eur. Heart J. - 2016. - Vol. 37, N 29. - P. 2315-2381. - doi: 10.1093/eurheartj/ehw106.


Review

For citations:


Mikhin V.P., Shveinov A.I., Kharchenko A.V., Vasilyeva D.A., Panchenko G.V., Gromnatsky N.I., Stepanets N.G. Influence of omega-3 unsaturated fatty acids on indices of diastolic left ventricular function in patients with acute coronary syndrome with outcome to acute myocardial infarction. Kursk Scientific and Practical Bulletin "Man and His Health". 2017;(4):46-51. (In Russ.) https://doi.org/10.21626/vestnik/2017-4/09

Views: 690


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1998-5746 (Print)
ISSN 1998-5754 (Online)