ROLE OF MEDICAL COMPLIANCE AND RELATED PSYCHOSOCIAL FACTORS IN PATIENTS WITH STROKE AND OTHER NEUROLOGICAL DISORDERS

Objective - to analyze and systematize the results of fundamental and clinical studies in recent years devoted to the study of the role of compliance and other psychosocial factors in the development of cerebral vascular catastrophe and other neurological disorders in adults.

Materials and methods. This thematic review includes available full-text publications obtained as a result of a literary search in the domestic (E-Library) Russian Science Citation Index (RSCI), as well as foreign databases (PubMed, Google Scholar, Semantic Scholar). In addition, studies conducted on the basis of the Smolensk State Medical University were analyzed.

Results. The role of compliance and other psychosocial factors in the occurrence and further progression of stroke, other neurological diseases, as well as some pathologies associated with other medical fields is significant and can be used for further study.

Conclusion. Based on the literature review, it can be concluded that the medical compliance of patients with neurological disorders is at a low level, which varies among different types of disorders. Most often, neurological patients do not follow the medication regimen due to forgetfulness, skipping doses outside the home and difficulties with taking medications. Patients who do not follow the medication regimen have low quality of life indicators, which requires further research and development of strategies to improve compliance, taking into account the specifics of neurological diseases.

1. Philip V. Peplow, Bridget Martinez, S.A. Dambinova.: Biomarkers of stroke. Moscow: GEOTAR Media, 2022 512 p. (in Russ.)

2. Feigin V.L., Norrving B., Mensah G.A. Global Burden of Stroke. Circ Res. 2017;120(3):439-448. DOI: 10.1161/CIRCRESAHA.116.308413.

3. Ignatyeva VI, Voznyuk I.A., Shamalov N.A., Reznik A.V., Vinitskiy A.A., Derkach E.V. Social and economic burden of stroke in Russian Federation. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(8-2): 5-15. (in Russ.). DOI: 10.17116/jnevro20231230825. EDN: QEIVCM.

4. Sui W., Wan L.H. Association Between Patient Activation and Medication Adherence in Patients With Stroke: A Cross-Sectional Study. Front Neurol. 2021;12:722711. DOI: 10.3389/fneur.2021.722711.

5. Babin S.M., Shlafer A.M.Compliance therapy for patients with schizophrenia. Moscow: Publishing house "Gorodets", 2020 160 p. (in Russ.)

6. Junaid Farrukh M., Makmor Bakry M., Hatah E., Hui Jan T. Medication adherence status among patients with neurological conditions and its association with quality of life. Saudi Pharm J. 2021;29(5):427-433. DOI: 10.1016/j.jsps.2021.04.003.

7. Shmonin A.A., Maltseva M.N., Melnikova Elena E. V., Ivanova G. E. Problems of adherence to drug therapy in medical rehabilitation. Doctor.Ru. 2017;11:20-27 (in Russ.). EDN: ZRXNAB.

8. Panova E.A., Serov V.A., Shutov A.M. Polypharmacy in Elderly Outpatients. Ulyanovsk Medical and Biological Journal. 2019;(2):16-22 (in Russ.). DOI: 10.34014/2227-1848-2019-2-16-22. EDN: QYQLCB.

9. Sychev D.A., Otdelenov V.A., Krasnova N.M., Ilyina E.S. Polypharmacy: a clinical pharmacologist’s view. Therapeutic Archives. 2016:88(12):94-102 (in Russ.). DOI: 10.17116/terarkh2016881294-102. EDN: XROGJZ.

10. Izmozherova N.V., Popov A.A., Kuryndina A.A., Gavrilova E.I., Shambatov M.A., Bakhtin V.M. Polymorbidity and polypharmacy in patients with high and very high cardiovascular risk. Rational Pharmacotherapy in Cardiology. 2022;18(1):20-26 (in Russ.). DOI: 10.20996/1819-6446-2022-02-09. EDN: CKVXKQ.

11. Franke G.H., Nentzl J., Jagla-Franke M., Prell T. Medication Adherence and Coping with Disease in Patients from a Neurological Clinic: An Observational Study. Patient Prefer Adherence. 2021;15:1439-1449. DOI: 10.2147/PPA.S311946.

12. Piradov M.A., Tanashyan M.M., Maksimova M.Y. Stroke: modern technologies of diagnosis and treatment. Moscow: MEDpress-inform, 2018, 354 p. (in Russ)

13. Palipudi K.M., Morton J., Hsia J., Andes L., Asma S., Talley B., Caixeta.RD., Fouad H., et al. Methodology of the Global Adult Tobacco Survey - 2008-2010. Glob Health Promot. 2016;23(2 Suppl):3-23. DOI: 10.1177/1757975913499800.

14. Kharakoz O.S., Kanorsky S.G., Shchelchkova I.S., Kizhvatova N.V. The first results of the Stroke Registry in Krasnodar. S.S. Korsakov Journal of Neurology and Psychiatry. 2001;101(2):26-30 (in Russ.). EDN: SSGZZH.

15. Galkin A.S., Minnullin T.I., Kovalchuck V.V., Fokina S.B., Stepanenko M.A., Barantcevich E.R., Gusev A.O., Samus N.L., Bogatyryova M.D. Possibilities of improving the effectiveness of rehabilitation of patients after stroke with neglect syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(10):30-34 (in Russ.). EDN: TGLSZF.

16. Golokhvastov S.Yu., Yanishevsky S.N., Tsygan N.V., Odinak M.M., Andreev R.V., Kolomentsev S.V., Skiba Ya.B.: Primary and secondary prevention of atherothrombotic stroke. Bulletin of the Russian Military Medical Academy. 2019;(S3):195-196 (in Russ.). EDN: MQEGPG.

17. Ambawatte S.B., Weerathunga D.N., Dissanayake A., Somaratne S.C., Athukorala K., Wijewickrama P.S.A. Ischemic Stroke Subtypes: Socio-demographic Factors, Risk Factors, and Outcomes in Southern Sri Lanka. Ethn Dis. 2021;31(4):509-518. DOI: 10.18865/ed.31.4.509.

18. Shmonin A. A., Maltseva M. N., Melnikova E. V., Ivanova G. E. Problems of adherence to drug therapy in medical rehabilitation. Doctor.Ru. 2017;(11):19-26 (in Russ.). EDN: ZRXNAB.

19. Aremu T.O., Oluwole O.E., Adeyinka K.O., Schommer J.C. Medication Adherence and Compliance: Recipe for Improving Patient Outcomes. Pharmacy (Basel). 2022;10(5):106. DOI: 10.3390/pharmacy10050106.

20. Prusiński T. When does doctor's recommendation become patient's resolution? The regulatory potential of procedural justice in the context of compliance with medical advice and the treatment process. Front Med (Lausanne). 2023;10:1004994. DOI: 10.3389/fmed.2023.1004994.