Comparative assessment of the performance properties of hemostatic applications implants
https://doi.org/10.21626/vestnik/2021-4/03
Abstract
Objective: to study the physical and mechanical properties of two-component spongy hemostatic implants. Materials and methods. Experimental group of two-component sample №1 based on Na-CMC was compared with samples: №3 Surgicel, №2 Tachocomb. To determine the residual strain, the specimens were compressed followed by fixation of the thickness recovery. To determine sorption capacity, the sample was weighed, placed in distilled water, transferred to a prepared test tube, centrifuged, and the sponge mass was measured. Porosity was determined in the same sequence, but the implants were immersed in orthoxylene. To determine adhesion, specimens were placed between two plates and the force of separation of the implant from the surface of the plate was recorded. Results. The porosity coefficient of specimen №1 was greater than №2 and №3 by 0.61 and 0.87. Adhesive properties of sample №1 are 0.28 greater than №2 and 0.45 greater than №3. The sorption capacity per unit mass of sample №1 is 2.5 times greater than №2 and 2.47 times greater than №3. The residual strain values of sample №1 and №2 were 1.18 and 2.87 less than №3. The values of sample №1 were higher than №2 by 1.69.
About the Authors
Alexander A. PanovRussian Federation
full-time graduate student of the Department of Operational Surgery and Topographic Anatomy, KSMU, Kursk, Russian Federatrion
Vyacheslav A. Lipatov
Russian Federation
Dr. Sci. (Med.), Professor, Professor of the Department of Operational Surgery and Topographic Anatomy, KSMU, Kursk, Russian Federatrion
Dmitry A. Severinov
Russian Federation
Cand. Sci. (Med.), Assistant of the Department of Pediatric Surgery and Pediatrics of the Institute of Continuing Education, KSMU, Kursk, Russian Federatrion
Artyom A. Denisov
Russian Federation
Assistant lecturer of the Department of Operational Surgery and Topographic Anatomy, KSMU, Kursk, Russian Federatrion
Vladimir N. Mishustin
Russian Federation
Dr. Sci. (Med.), Professor of the Department of Surgical Diseases of the Institute of Continuing Education, KSMU, Kursk, Russian Federatrion
References
1. Baruzdina E.S., Oshurkova U.L. Features of hemostasis system in old dog. Veterinary pathology. 2016;1(55):69-74 (in Russ.)
2. Garayev I.Kh., Musin I.N., Zenitova L.A. Antiseptic bandaging materials based on sphagnum. Medical Science Bulletin. 2019;1(13): 7-12. DOI: 10.31684/2541-8475.2019
3. Gorsky V.A., Zryanin A.M., Agapov M.A. The effectiveness of TachoComb use in hepatobiliary surgery. Modern technologies in medicine. 2011;(2):61-68 (in Russ.)
4. Zarivchatsky M.F., Mugatarov I.N., Kamenskikh E.D., Gavrilov O.V., Malginov K.E., Kolevatov A.P., Pankov K.I. Hemorrhage prevention and compensation in hepatic resection surgery. Perm medical journal. 2013;30(5):6-12 (in Russ.)
5. Leonov D.V., Rozov R.M., Ustinova T.P., Klyuev I.A. Study of the physical and mechanical properties of polyamide-6 modified with oxidized graphite and basalt wool at the stage of its synthesis. Molodoy uchenyy. 2015;24(1):38-40 (in Russ.)
6. Lipatov V.A., Inrow M.A., Yarmamedov D.M., Lisansky K.V Morphological and physico-mechanical properties polymeric membranous implants in vitro. Transbaikalian medical bulletin. 2015;(1):129-133 (in Russ.)
7. Lipatov V.A., Severinov D.A., Sahakyan A.R. Local hemostatics in surgery of the 21st century. INNOVA. 2019;1(14):16-22 (in Russ.). DOI: 10.21626/innova/2019.1/03
8. Alam H.B., Burris D., DaCorta J.A., Rhee P. Hemorrhage control in the battlefield: role of new hemostatic agents. Mil Med. 2005;170(1):63-69. DOI: 10.7205/milmed.170.1.63
9. Bak J.B., Singh A., Shekarriz B. Use of gelatin matrix thrombin tissue sealant as an effective hemostatic agent during laparoscopic partial nephrectomy. J Urol. 2004;171(2 Pt 1):780-782. DOI: 10.1097/01.ju.0000104800.97009.c6
10. Barker T.H., Fuller G.M., Klinger M.M., Feldman D.S., Hagood J.S. Modification of fibrinogen with poly(ethylene glycol) and its effects on fibrin clot characteristics. J Biomed Mater Res. 2001;56(4): 529-535. DOI: 10.1002/1097-4636(20010915)56:4<529::aid-jbm1124>3.0.co;2-2
11. Briceño J., Naranjo A., Ciria R., Díaz-Nieto R., Sánchez-Hidalgo J.M., Luque A., Rufián S., López-Cillero P. A prospective study of the efficacy of clinical application of a new carrier-bound fibrin sealant after liver resection. Arch Surg. 2010;145(5):482-488. DOI: 10.1001/archsurg.2010.62
12. Hanna E.M., Martinie J.B., Swan R.Z., Iannitti D.A. Fibrin sealants and topical agents in hepatobiliary and pancreatic surgery: a critical appraisal. Langenbecks Arch Surg. 2014;399(7):825-835. DOI: 10.1007/s00423-014-1215-5
13. Kim Y.W., Kang M.J., Lee H.J., Woo C.K., Mun M.J., Cho K.S. The efficacy of TachoComb on reducing postoperative complications after tonsillectomy in children.Int J Pediatr Otorhinolaryngol. 2015;79(8):1337-1340. DOI: 10.1016/j.ijporl.2015.06.006
14. Nair L.S., Laurencin C.T. Biodegradable polymers as biomaterials. Prog Polym Sci. 2007;32(8-9):762-798. DOI: 10.1016/j.progpolymsci.2007.05.017
Review
For citations:
Panov A.A., Lipatov V.A., Severinov D.A., Denisov A.A., Mishustin V.N. Comparative assessment of the performance properties of hemostatic applications implants. Humans and their health. 2021;24(4):17-23. (In Russ.) https://doi.org/10.21626/vestnik/2021-4/03