Changing in antioxidant protective status after introducing apoptosis-induced mesenchymal stem cells against the background of experimental acute renal failure
Abstract
The study of antioxidant activity in animals after simulating experimental renal failure revealed the decrease in the level of system principle enzymes, namely superoxide dismutase and catalase on the 7th and 14th days of the study. These results may indicate a decrease in antioxidant protective abilities and the activation of lipid peroxidation in tissues of the organ examined. The subsequent introduction of the mesenchymal stem cells grown in apoptosis-induced environment led to the increased level of the enzymes studied in renal tissue comparing to the control group of animals on these days and comparing to intact animals by the14th day of the experiment.
About the Authors
A. A. Chebotareva
Kursk State Medical University, Kursk
Russian Federation
Russian Federation
I. A. Komarevtseva
Lugansk State Medical University, Lugansk, Ukraine
Russian Federation
Russian Federation
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Review
For citations:
Chebotareva A.A., Komarevtseva I.A. Changing in antioxidant protective status after introducing apoptosis-induced mesenchymal stem cells against the background of experimental acute renal failure. Kursk Scientific and Practical Bulletin "Man and His Health". 2015;(3):101-104. (In Russ.)
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