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Studying the characteristics of the qualitative composition of essential oil of hops of ordinary co-fruits of natural phytocenosis of Voronezh region

https://doi.org/10.21626/vestnik/2024-2/07

EDN: VFNIQI

Abstract

Currently, in the Voronezh region, it is planned to develop large-scale cultivation and harvesting of hops of ordinary coproducts, one of the main groups of biologically active substances of which is essential oils. The formation and accumulation of biologically active substances in plants is a complex process associated with a number of climatic, soil, environmental and other factors. Objective - study of the component composition of the essential oil of hops of ordinary coproducts harvested from wild plants in the natural ecotope of the Voronezh region. Materials and methods. In the Voronezh region, hops of ordinary co-fruit were harvested in a natural ecotope in an ecologically clean place in accordance with the requirements of regulatory documentation. The preparation of the hop essential oil of common coproducts and the quantification of its content were carried out by hydroparodistillation. Component composition of the obtained essential oils was determined using Agilent Technologies 7890B GC System (Agilent Technologies, USA) with Agilent Technologies 5977A MSD mass selective detector (Agilent Technologies, USA). Data analysis and processing was carried out on the basis of NIST11 databases (from 19.05.2011), MassHunter v. B.06.00 and NIST MS Search 2.0 software were used. Results. Significant raw materials reserves of hops of common coproducts in the territory of the Central Black Earth Region make relevant both the procurement of wild raw materials and the development of its cultivation in the region for food and pharmaceutical needs. The studied features of the accumulation of the main components of essential oil of common hop co-fruits can be taken into account in the cultivation and procurement of raw materials. Conclusion. Significant raw materials reserves of hops of common coproducts in the territory of the Central Black Earth Region make relevant both the procurement of wild raw materials and the development of its cultivation in the region for food and pharmaceutical needs. The studied features of the accumulation of the main components of essential oil of common hop co-fruits can be taken into account in the cultivation and procurement of raw materials.

References

1. Putyrskij I.N., Prohorov V.N. Hmel' obyknovennyj. Lekarstvennye. Minsk: Knizhnyj dom; 2005. 704 c. (in Russ.)

2. Kurkin V.A. Pharmacognosy. Samara: Ofort; 2004. 1179 p. (in Russ.)

3. Chadwick L.R., Pauli G.F., Farnsworth N.R. The pharmacognosy of Humulus lupulus L. (hops) with an emphasis on estrogenic properties. Phytomedicine. 2006;13(1-2):119-131.

4. State Pharmacopoeia of the Russian Federation. Edition XIV. Volume 4. Moscow: FEMB; 2018:1883 (in Russ.)

5. Akazawa H., Kohno H., Tokuda H., Suzuki N., Yasukawa K., Kimura Y., Manosroi A., Manosroi J., Akihisa T. Anti-inflammatory and anti-tumor-promoting effects of 5-deprenyllupu-lonol C and other compounds from Hop (Humulus lupulus L.). Chemistry and Biodiversity. 2012;9(6):1045-1054.

6. Albini A., Dell'Eva R., Vené R., Ferrari N., Buhler D.R., Noonan D.M., Fassina G. Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets. FASEB Journal. 2006;20(3):527-529.

7. Wang X., Yang L., Yang X., Tian Y. In vitro and in vivo antioxidant and antimutagenic activities of polyphenols extracted from hops (Humulus lupulus L.). Journal of the Science of Food and Agriculture. 2014;94(8):1693-1700. DOI: 10.1002/jsfa.6534.

8. Chadwick L.R., Nikolic D., Burdette J.E., Overk C.R., Bolton J.L., van Breemen R.B., Frohlich R., Fong H.H., Farnsworth N.R., Pauli G.F. Estrogens and congeners from spent hops (Humulus lupulus). Journal of Natural Products. 2004;67(12):2024-2032.

9. Pinto C., Cestero J.J., Rodríguez-Galdón B., Macías P. Xanthohumol, a prenylated flavonoid from hops (Humulus lupulus L.), protects rat tissues against oxidative damage after acute ethanol administration. Toxicology Reports. 2014;1:726-733. DOI: 10.1016/j.toxrep.2014.09.004.

10. Monteiro R., Becker H., Azevedo I., Calhau C. Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity - Journal of Agricultural and Food Chemistry. 2006;54(8):2938-2943.

11. Kyrou I., Christou A., Panagiotakos D., Stefanaki C., Skenderi K., Katsana K., Tsigos C. Effects of a hops (Humulus lupulus L.) dry extract supplement on self-reported depression, anxiety and stress levels in apparently healthy young adults: a randomized, placebo-controlled, double-blind, crossover pilot study. Hormones (Athens). 2017;16(2):171-180. DOI: 10.14310/horm.2002.1738.

12. Franco L., Sánchez C., Bravo R., Rodriguez A., Barriga C., Juánez J.C. The sedative effects of hops (Humulus lupulus), a component of beer, on the activity/rest rhythm. Acta Physiologica Hungarica. 2012;99(2):133-139. DOI: 10.1556/APhysiol.99.2012.2.6.

13. Miyashita M., Sadzuka Y. Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor activity. Food and Chemical Toxicology. 2013;53:174-179. DOI: 10.1016/j.fct.2012.11.035.

14. Li Z.J., Li Z., Dong X.Y., Lu L.F., Wang C.L. Hypouricemic and nephroprotective effects of total flavonoids from the residue of supercritical CO2 extraction of Humulus lupulus in potassium oxonate-induced mice. Pakistan Journal of Pharmaceutical Sciences. 2017;30(2):493-497.

15. Langezaal C.R., Chandra A., Scheffer J.J. Antimicrobial screening of essential oils and extracts of some Humulus lupulus L. cultivars. Pharmaceutisch Weekblad Scientific Edition. 1992;14(6):353-356.

16. Dietz B.M., Hagos G.K., Eskra J.N., Wijewickrama G.T., Anderson J.R., Nikolic D., Guo J., Wright B., et al. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. Molecular Nutrition & Food Research. 2013;57(6):1055-1066. DOI: 10.1002/mnfr.201200534.

17. Figard H., Girard C., Mougin F., Demougeot C., Berthelot A. Effects of aqueous hop (Humulus Lupulus L.) extract on vascular reactivity in rats: mechanisms and influence of gender and hormonal status. Phytomedicine. 2008;15(3):185-193.

18. Frolich S., Schubert C., Bienzle U., Jenett-Siems K. In vitro antiplasmodial activity of prenylated chalcone derivatives of hops (Humulus lupulus) and their interaction with haemin. Journal of Antimicrobial Chemotherapy. 2005;55(6):883-887.

19. Karomatov I.D., Atamuradova SH.T. Pishchevoe i lechebnoe znachenie rasteniya hmel' obyknovennyj. Biologiya i integrativnaya medicina. 2018;18(1):187-212 (in Russ.). EDN: XTSQYX.

20. Registr lekarstvennyh sredstv Rossii. URL: https://www.rlsnet.ru/(in Russ.)

21. Hunsel F.P., Koppel S., Puijenbroek E. Post-Menopausal Vaginal Hemorrhage Related to the Use of a Hop-Containing Phytotherapeutic Product. Drug Safety - Case Reports. 2015;2(1):14.

22. Hunsel F.P., Kampschöer P. Postmenopausal bleeding and dietary supplements: a possible causal relationship with hop- and soy-containing preparations. Nederlands Tijdschrift voor Geneeskunde. 2012;156(41):A5095.

23. Latypova G.M. Eksperimental'no-teoreticheskoe obosnovanie racional'nogo ispol'zovaniya rastenij roda Primula L. i roda Humulus L.: avtoreferat diss. … d-ra farm. nauk: 14.04.02. Samara, 2015:46. (in Russ.)

24. Zhang W.K., Wang S.B., Fu C.Y., Li P., Xu J.K. Flavonoids from Humulus lupulus. Zhongguo Zhong Yao Za Zhi. 2013;38(10):1539-1542.

25. Wang W.S., Ye Y.H., Zhou Y.W. New prenylchalcones from the hops of Humulus luputus. Journal of Asian Natural Products Research. 2008;10(5-6):485-490.

26. Zhang N., Tian B., Zhao S., Zhang X., Pan D., Shen X., Zhang Y. A new formylated chalcone from Humulus lupulus with protective effect on HUVECs injury by angiotensin II. Journal of Asian Natural Products Research. 2017;24:1-5. DOI: 10.1080/14786419.2017.1402318.

27. Lin L.Y., Jiang Y.P., Zhang Q.Y., Qin L.P., Xin H.L. Research progress of chemical constituents and pharmacological activities in Humulus lupulus. Zhongguo Zhong Yao Za Zhi. 2017;42(10):1825-1829. DOI: 10.19540/j.cnki.cjcmm.20170224.016.

28. Bohr G., Gerhauser C., Knauft J., Zapp J., Becker H. Anti-inflammatory acylphloroglucinol derivatives from Hops (Humulus lupulus). Journal of Asian Natural Products Research. 2005;68(10):1545-1548.

29. Forino M., Pace S., Chianese G., Santagostini L., Werner M., Weinigel C., Rummler S., Fico G., Werz O., Taglialatela-Scafati O. Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "Cascade"). Journal of Asian Natural Products Research. 2016;79(3):590-597. DOI: 10.1021/acs.jnatprod.5b01052.

30. Gedrajtite G. The content of bitter substances and essential oil in hop cones from different ecotopes of Lithuania and their biometric indicators. Biologija. 1996;1:69-73.

31. Sokolova L.S., Pavlova E.V., SHushenacheva A.M., Efremov A.A. Osobennosti komponentnogo sostava efirnogo masla nadzemnoj chasti Phlomis tuberose L. i Humulus lupulus L. Himiya rastitel'nogo syr'ya. 2012;(2):101-104 (in Russ.). EDN: PJTOIJ.

32. D'yakova N.A., Korenskaya I.M., Kostyleva A.A., Slivkin A.I., Gaponov S.P. Izuchenie osobennostej nakopleniya efirnogo masla v lekarstvennyh rasteniyah razlichnyh ekologicheskih uslovij proizrastaniya. Vestnik Smolenskoj medicinskoj akademii. 2023;22(2):207-214 (in Russ.). DOI: 10.37903/vsgma.2023.2.28. EDN: PLYRPZ.

33. D'yakova N.A., Korenskaya I.M., Slivkin A.I. Sravnitel'nyj analiz kachestvennogo sostava efirnogo masla travy polyni gor'koj sinantropnoj flory Voronezhskoj oblasti. Razrabotka i registraciya lekarstvennyh sredstv. 2023;12(2):104-112 (in Russ.). DOI: 10.33380/2305-2066-2023-12-2-104-112. EDN: IPFKJK.

34. D'yakova N.A., Korenskaya I.M., Slivkin A.I., Gaponov S.P. Izuchenie osobennostej kolichestvennogo i kachestvennogo sostava efirnogo masla travy tysyachelistnika obyknovennogo flory Voronezhskoj oblasti. Himiko-farmacevticheskij zhurnal. 2022;56(9):37-44 (in Russ.). DOI: 10.30906/0023-1134-2022-56-9-37-44. EDN: UQKLUN.

35. V proekt po vyrashchivaniyu i pererabotke hmelya pod Voronezhem mogut napravit' bolee 17 mlrd rublej. URL: https://www.kommersant.ru/doc/5797493 (in Russ.)

36. Adams R.P. Identification of essential oil components by gas chromatography/mass spectrometry. 4th ed. Carol Stream: Allured Publ. Corp.; 2007:804.

37. Hejfic L.A., Dashunin V.M. Dushistye veshchestva i drugie produkty dlya parfyumerii. Moskva: Himiya; 1994. 256 p. (in Russ.)

38. Bouzabata A., Cassanova J., Bighelli A., Cavaleiro C., Salgueiro L., Tomi F. The Genus Myrtus L. in Algeria: Composinion and Biological Aspects of Essential Oils from M.communis and M. nivellei: A Review. Chemistry and Biodiversity. 2016;13(6):672-680.

39. Rufino S.M., Alves R.E., de Brito E.S., Pérez-Jiménes J., Saura-Calixto F., Mancini-Filho J. Bioactive compounds and antioxidant capacities of 18 non-traditional tropical fruits from Brazil. Food Chemistry. 2010;121(4):996-1002.

40. Hetka N., Subach V., Rogovoy P.Comparative studies in leaf volatile compounds of three Cinnamomum species cultivated in greenhouses of Belarus. Book of abstracts of 11 th Symp. on the Flora of Southeastern Serbia and Neighboring Regions. Vlasina. 2013: 103-104.

41. Surendran S., Qassadi F., Surendran G., Lilley D., Heinrich M. Myrcene - What Are the Potential Health Benefits of This Flavouring and Aroma Agent? Frontiers in Nutrition. 2022;8:666-669. DOI: 10.3389/fnut.2021.699666.


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For citations:


Korenskaya I.M., Dyakova N.A. Studying the characteristics of the qualitative composition of essential oil of hops of ordinary co-fruits of natural phytocenosis of Voronezh region. Humans and their health. 2024;27(2):54-62. (In Russ.) https://doi.org/10.21626/vestnik/2024-2/07. EDN: VFNIQI

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