Structural organization of the complex "lumbar vertebrae and paravertebral muscles" of people aged 35-59 years according to results of factor analysis by the method of principal components

Objective - to find sexual and age differences of the lumbar vertebrae and paravertebral muscles array structural organization. Materials and methods. Computed tomograms of the lumbar spine of 220 women (19 aged 35-44 years and 201 aged 45-59 years) and 147 men (15 aged 35-44 years and 132 aged 45-59 years) were used. At each segment of the vertebrae-paravertebral muscles there are 12 parameters were measured. Nonparametric statistics and factor analysis by the principal component method also were used. Results. Direct measurements of the vertebrae show the presence of sexual differences in the width, height and length of the vertebral bodies in the L1-L3 segments. Significant differences were revealed (at p=0.01) between the vertebral sizes in men and women aged 35-44 years in the length of the L2 vertebral body (in women 3.44-3.96 cm, in men 3.73-4.07 cm). The dependence of changes in the size of the vertebrae (p<0.05) in women in the length of the vertebral opening in the L1 segment, in men in the lower body width of the vertebrae L2, L4, upper body width of the L4 vertebra, the length of the spinous process L2, the angle of its incline in L3. The structural organization of the complex "lumbar vertebrae-paravertebral muscles" in representatives of different sexes are different. In women aged 35-44 years, 8 parameters play a key role, in men - 26, with age in men it decreases to 14. In women, age adjustment is associated with the redistribution of factor loads and the preservation of their number, in men it is accompanied by a decrease in the number of parameters involved. Conclusion. The structural organization of the complex "lumbar vertebrae - paravertebral muscle arrays" has a well pronounced sexual dimorphism. Age-related differences of the both sexes structural organization proceed differently; the initially more adapted men's "vertebral column - paravertebral muscles" system undergoes changes with age, manifested by rising it's structurality.

1. Anisimova E.A Patterns of variability in the size and shape of the vertebrae of the precostal spine. Izvestiya vysshih uchebnyh zavedenij. Povolzhskij region. Medicinskie nauki. 2009;2(10):3-13. (in Russ.). EDN: LAKOWH.

2. Sewell W., Kusumi K. Birth Genetic analysis of molecular oscillators in mammalian somitogenesis: clues for studies of human vertebral disorders. Defects Res C Embryo Today. 2007;81(2):111-120. DOI: 10.1002/bdrc.20091.

3. Snodgrass J.J. Sex differences and aging of the vertebral column. J Forensic Sci. 2004;49(3):458-463.

4. Prescher A. Anatomy and pathology of the aging spine. Eur J Radiol. 1998;27(3):181-195. DOI: 10.1016/s0720-048x(97)00165-4.

5. Rühli F.J., Müntener M., Henneberg M. Age-dependent changes of the normal human spine during adulthood. Am J Hum Biol. 2005;4:460-469. DOI: 10.1002/ajhb.20403.

6. Poorghasamians E., Aggabao P.C., Wren TAL, Ponrartana S., Gilsanz V. Vertebral cross-sectional growth: A predictorof vertebral wedging in the immature skeleton. PLoS One. 2017;12:e0190225. DOI: 10.1371/journal.pone.0190225.

7. Rojas C.V., Olivares J.I., Tutor P.M., Sánchez M., Alemán Aguilera I. Ontogeny of morphological variations in the vertebral column: Prevalence and bony variability in young Spanish children. Ann Anat. 2022;240:151888. DOI: 10.1016/j.aanat.2022.151888.

8. Gilsanz V., Wren TAL, Ponrartana S., Mora S., Rosen C.J. Sexual Dimorphism and the Origins of Human Spinal Health. Endocr Rev. 2018;39(2): 221-239. DOI: 10.1210/er.2017-00147.

9. Yadgarov M.YA., Berikashvili L.B., Kadanceva K.K., Kuzovlev A.N., Perekhodov S.N., Lihvancev V.V. Multivariate analysis in clinical medicine. Anesteziologiya i reanimatologiya. 2021;1(5): 64-70 (in Russ.). DOI: 10.17116/anaesthesiology202105164. EDN: SAUUXM.

10. Yashina I.N., Ivanov A.V., Ivanov M.A., Samaha A.A. Systemic organization of the human humerus. Morfologiya. 2019;155(1):40-47 (in Russ.). EDN: KIVYG.

11. Ivanov M.A., Yashina I.N., Klochkova S.V., Yashin F.D. System relationships of the thoracic vertebrae anatomy and surrounding muscles in overweight men. Humans and their health. 2023;26(4):65-71 (in Russ.). DOI: 10.21626/vestnik/2023-4/05. END: LOFUWQ.

12.

13. Емкужев О.Л., Анисимова Е.А., Щуковский В.В., Анисимов Д.И. Изменчивость абсолютных и относительных размеров тел поясничных позвонков. Современные проблемы науки и образования. 2015;(6):141. EDN: VJPROX. URL: https://science-education.ru/ru/article/view?id=23331 (дата обращения: 18.06.2024)

14. @@ Emkuzhev O.L., Anisimova E.A., Shchukovskij V.V., Anisimov D.I. Variability of absolute and relative size of lumbar vertebral bodies. Sovremennye problemy nauki i obrazovaniya. 2015;(6):141 (in Russ.). EDN: VJPROX. URL: https://science-education.ru/ru/article/view?id=23331 (дата обращения: 18.06.2024)