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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kurskvest</journal-id><journal-title-group><journal-title xml:lang="ru">Человек и его здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Humans and their health</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5746</issn><issn pub-type="epub">1998-5754</issn><publisher><publisher-name>Kursk State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21626/vestnik/2021-4/05</article-id><article-id custom-type="elpub" pub-id-type="custom">kurskvest-974</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Особенности ремоделирования миокарда у пациентов различных возрастных групп через 6 месяцев после перенесенного инфаркта миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Peculiarities of myocardial remodeling in patients of different age groups 6 months after myocardial infarction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1122-1816</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Букатов</surname><given-names>Владислав Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Bukatov</surname><given-names>Vladislav V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-кардиолог палаты реанимации и интенсивной терапии отделения неотложной кардиологии, БОКБ, г. Белгород</p></bio><bio xml:lang="en"><p>cardiologist of the Resuscitation and Intensive Care unit of the Emergency Cardiology Department, BRCH, Belgorod, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7321-6529</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипова</surname><given-names>Ольга Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Osipova</surname><given-names>Olga A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, доцент, зав. кафедрой госпитальной терапии, БелГУ, г. Белгород</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Associate Professor, Head of the Department of Hospital Therapy, BSU, Belgorod, Russian Federation</p></bio><email xlink:type="simple">osipova_75@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белгородская областная клиническая больница Святителя Иоасафа (БОБК)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belgorod Regional Clinical Hospital of St. Joasaph (BRCH)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белгородский государственный национальный исследовательский университет (БелГУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belgorod State National Research University (BSU)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2021</year></pub-date><volume>24</volume><issue>4</issue><fpage>34</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Букатов В.В., Осипова О.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Букатов В.В., Осипова О.А.</copyright-holder><copyright-holder xml:lang="en">Bukatov V.V., Osipova O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.kursk-vestnik.ru/jour/article/view/974">https://www.kursk-vestnik.ru/jour/article/view/974</self-uri><abstract><p>Цель - оценить характер изменений типов ремоделирования миокарда левого желудочка у пациентов с острым инфарктом миокарда с подъемом сегмента ST, среднего, пожилого и старческого возраста в течение 6 месяцев после успешной реваскуляризации. Материалы и методы. В исследование включены 132 пациента с острым инфарктом миокарда с подъемом сегмента ST, Killip I в сочетании с артериальной гипертензией (длительность артериальной гипертензии от 5 до 30 лет), которые были распределены на 3 возрастные группы: пациенты среднего возраста (45-59 лет) - 48 человек, пациенты пожилого возраста (60-74 года) - 44 человека, пациенты старческого возраста (75-89 лет) - 40 человек. У пациентов методом допплер-эхокардиографии оценивался тип ремоделирования левого желудочка с определением относительной толщины стенки и индекса массы миокарда левого желудочка в первые 12 часов с момента развития ангинозного синдрома, и через 6 месяцев на фоне традиционной медикаментозной терапии. Всем пациентам выполнено чрескожное коронарное вмешательство, стентирование в первые 12 часов от начала ангинозного приступа. Результаты. Установлено, что исходно при развитии острого инфаркта миокарда пациенты старческого возраста чаще имели эксцентрическую гипертрофию левого желудочка (25%), чем пациенты среднего (6%) и пожилого возраста (11%). Через 6 месяцев у пациентов среднего возраста тип ремоделирования эксцентрическая гипертрофия вырос до 14%, у пожилых до 23%, у пациентов старческого возраста до 50%. Заключение. У больных, перенесших острый инфаркт миокарда, на фоне традиционной терапии и реабилитации имеют место изменения типов ремоделирования миокарда ЛЖ: возрастает эксцентрическая гипертрофия у среднего возраста до 14%, у пожилого до 23%, у старческого до 50%. Пациенты пожилого и, в особенности, старческого возраста в отдаленный период после острого инфаркта миокарда имеют высокие риски развития типа ремоделирования миокарда левого желудочка эксцентрическая гипертрофия.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To assess the nature of changes in the types of myocardial remodeling of the left ventricle in patients of middle, elderly and senile age with acute ST-segment elevation myocardial infarction within 6 months after successful revascularization. Materials and methods. The study included 132 patients with a diagnosis of acute ST-segment elevation myocardial infarction, in combination with arterial hypertension who were divided into 3 groups depending on age: middle-aged patients (45- 59) - 48 people, elderly patients (60-74) - 44 people, senile patients (75-89) - 40 people. The type of left ventricular remodeling was assessed by determining the relative wall thickness and mass index of the left ventricular myocardium with doppler echocardiography in the first 12 hours after the onset of anginal syndrome, and after 6 months. All patients underwent percutaneous coronary intervention. Results. It was found that initially with the development of acute myocardial infarction, senile patients more often had eccentric left ventricular hypertrophy (in 25%) than patients of middle (6%) and elderly age (11%). After 6 months, in middle-aged patients, the type of remodeling eccentric hypertrophy increased to 14%, in the elderly - up to 23%, in senile patients - up to 50%. Conclusion. In patients who have undergone acute myocardial infarction against the background of traditional therapy and rehabilitation, there are changes in the types of left ventricular myocardial remodeling: eccentric hypertrophy increases in middle age up to 14%, in the elderly - up to 23%, in senile age - up to 50%.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>ремоделирование миокарда</kwd><kwd>хроническая сердечная недостаточность</kwd><kwd>пациенты пожилого и старческого возраста</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>myocardial remodeling</kwd><kwd>chronic heart failure</kwd><kwd>elderly and senile patients</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бабушкина Г.В., Пермякова С.В., Губаева А.М. Прогностические маркеры тяжести постинфарктного течения у пациентов трудоспособного возраста, перенесших Q-инфаркт миокарда. Медицинский алфавит. 2020;(21):76-80. DOI: 10.33667/2078-5631-2020-21-76-80</mixed-citation><mixed-citation xml:lang="en">Babushkina, G.V., Permyakova S.V., Gubayeva A.M. Predictive markers of severity ofpostinfarction in patients of working age who have had Q-myocardial infarction. Medical alphabet. 2020;(21):76-80 (in Russ.). DOI: 10.33667/2078-5631-2020-21-76-80</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Букатов В.В. Клинико-анамнестические, лабораторно-инструментальные, структурно-функциональные особенности пациентов старших возрастных групп через 6 месяцев после перенесенного инфаркта миокарда. Актуальные проблемы медицины. 2021;44(3):332-342. DOI: 10.52575/2687-0940-2021-44-3-332-342</mixed-citation><mixed-citation xml:lang="en">Bukatov V.V. Clinical-anamnestic, laboratory-instrumental, structural and functional peculiarities of older age patients 6 months after myocardial infarction. Challenges in modern medicine. 2021;44(3):332-342 (in Russ.). DOI: 10.52575/2687-0940-2021-44-3-332-342</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Калюжин В.В., Тепляков А.Т., Соловцов М.А., Калюжина Е.В., Беспалова И.Д., Терентьева Н.Н. Ремоделирование левого желудочка: один или несколько сценариев? Бюллетень сибирской медицины. 2016;15(4):120-139. DOI: 10.20538/1682-0363-2016-4-120-13</mixed-citation><mixed-citation xml:lang="en">Kalyuzhin V.V., Teplyakov A.T., Solovtsov M.A., Kalyuzhina E.V., Bespalova I.D., Terentyeva N.N. Remodeling of the left ventricle: one or several scenarios? Bulletin of Siberian Medicine. 2016;15(4):120-139. (in Russ.). DOI: 10.20538/1682-0363-2016-4-120-139</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Керчева М.А., Рябова Т.Р., Гусакова А.М. Неблагоприятное ремоделирование левого желудочка и сывороточный уровень матриксных металлопротеиназ, маркеров миокардиальной дисфункции и субклинического воспаления у пациентов с острым первичным передним инфарктом миокарда с подъемом сегмента ST. Сибирский медицинский журнал (г. Томск). 2018;41(1):31-35</mixed-citation><mixed-citation xml:lang="en">Kercheva M.A., Ryabova T.R., Gusakova A.M. Adverse left ventricular remodeling and the serum levels of matrix metalloproteinases, biomarkers of myocardium dysfunction and inflammation in patients with acute primary anterior STEMI. The Siberian Medical Journal. 2018;41(1):31-35. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Осипова О.А., Букатов В.В. Особенности течения инфаркта миокарда с подъемом сегмента ST у больных пожилого и старческого возраста. Научные результаты биомедицинских исследований. 2020;6(3):402-416. DOI:10.18413/2658-6533-2020-6-3-0-10</mixed-citation><mixed-citation xml:lang="en">Osipova O.A. Bukatov V.V. Features of myocardial infarction with ST segment elevation in patients of the older age group. Research results in biomedicine. 2020;6(3):402-416 (in Russ.). DOI:10.18413/2658-6533-2020-6-3-0-10</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Фролов А.А., Кузьмичев К.В., Починка И.Г., Шарабрин Е.Г., Савенков А.Г. Влияние поздней реваскуляризации инфаркт-ответственной коронарной артерии на прогноз при инфаркте миокарда с подъемом сегмента ST. Российский кардиологический журнал. 2020;25(8):54-59. DOI: 10.15829/1560-4071-2020-3796</mixed-citation><mixed-citation xml:lang="en">Frolov A.A., Kuzmichev K.V., Pochinka I.G., Sharabrin E.G., Savenkov A.G. Effect of late culprit coronary artery revascularization on prognosis of patients with ST-elevation myocardial infarction.Russian journal of cardiology. 2020;25(8):54-59 (in Russ.). DOI: 10.15829/1560-4071-2020-3796</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Шеховцова Л.В., Осипова О.А., Головин А.И., Плаксина К.Г., Должиков А.А. Влияние методов фармакотерапии на ремоделировании миокарда левого желудочка сердца у больных острым инфарктом миокарда после перенесенной реперфузии в профилаткике формирования ХСН. Научные ведомости Белгородского государственного университета. Серия: Медицина. Фармация. 2018;41(4):519-527. DOI: 10.52575/2687-0940-2021-44-3-332-342</mixed-citation><mixed-citation xml:lang="en">Shekhovtsova L.V., Osipova O.A., Golovin A.I., Plaksina K.G., Dolzhikov A.A. Influence of methods of pharmacotherapy in myocardial remodeling of the left ventricle in patients with acute myocardial infarction after reperfusion in the prevention of the formation of CHF. Scientific bulletins of Belgorod State University. Series: Medicine. Pharmacia. 2018;41(4):519-527 (in Russ.). DOI: 10.52575/2687-0940-2021-44-3-332-342</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Balitskya A., Klester E.B., Klester K.V., Yarkova V., Nikitin V. Heart remodeling in patients after ST-segment elevation myocardial infarction with and without concomitant COPD. Eur Respir J. 2020;56(S64):549. DOI: 10.1183/13993003.congress-2020.549</mixed-citation><mixed-citation xml:lang="en">Balitskya A., Klester E.B., Klester K.V., Yarkova V., Nikitin V. Heart remodeling in patients after ST-segment elevation myocardial infarction with and without concomitant COPD. Eur Respir J. 2020;56(S64):549. DOI: 10.1183/13993003.congress-2020.549</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Erne P., Radovanovic D., Schoenenberger A.W., Bertel O., Kaeslin T., Essig M., Gaspoz J.M.; AMIS Plus Investigators. Impact of hypertension on the outcome of patients admitted with acute coronary syndrome. J Hypertens. 2015;33(4):860-867. DOI: 10.1097/HJH.0000000000000343</mixed-citation><mixed-citation xml:lang="en">Erne P., Radovanovic D., Schoenenberger A.W., Bertel O., Kaeslin T., Essig M., Gaspoz J.M.; AMIS Plus Investigators. Impact of hypertension on the outcome of patients admitted with acute coronary syndrome. J Hypertens. 2015;33(4):860-867. DOI: 10.1097/HJH.0000000000000343</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ertaş F.S., Tokgözoğlu L.; EPICOR Study Group. Pre- and in-hospital antithrombotic management patterns and in-hospital outcomes in patients with acute coronary syndrome: data from the Turkish arm of the EPICOR study. Anatol J Cardiol. 2016;16(12):900-915. DOI: 10.14744/AnatolJCardiol.2016.6755</mixed-citation><mixed-citation xml:lang="en">Ertaş F.S., Tokgözoğlu L.; EPICOR Study Group. Pre- and in-hospital antithrombotic management patterns and in-hospital outcomes in patients with acute coronary syndrome: data from the Turkish arm of the EPICOR study. Anatol J Cardiol. 2016;16(12):900-915. DOI: 10.14744/AnatolJCardiol.2016.6755</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Goldbergova M.P., Parenica J., Jarkovsky J., Kala P., Poloczek M., Manousek J., Kluz K., Kubkova L. et al. The association between levels of tissue inhibitor of metalloproteinase-1 with acute heart failure and left ventricular dysfunction in patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention. Genet Test Mol Biomarkers. 2012;16(10):1172-1178. DOI: 10.1089/gtmb.2012.0120</mixed-citation><mixed-citation xml:lang="en">Goldbergova M.P., Parenica J., Jarkovsky J., Kala P., Poloczek M., Manousek J., Kluz K., Kubkova L. et al. The association between levels of tissue inhibitor of metalloproteinase-1 with acute heart failure and left ventricular dysfunction in patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention. Genet Test Mol Biomarkers. 2012;16(10):1172-1178. DOI: 10.1089/gtmb.2012.0120</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kocayigit I., Yaylaci S., Osken A., Aydın E., Sahinkus S., Can Y., Genc A.B., Gunduz H.Comparison of effects of thrombolytic therapy and primary percutaneous coronary intervention in elderly patients with acute ST-segment elevation myocardial infarction on in-hospital, six-month, and one-year mortality. Arch Med Sci Atheroscler Dis. 2019;4:e82-e88. DOI: 10.5114/amsad.2019.85378</mixed-citation><mixed-citation xml:lang="en">Kocayigit I., Yaylaci S., Osken A., Aydın E., Sahinkus S., Can Y., Genc A.B., Gunduz H.Comparison of effects of thrombolytic therapy and primary percutaneous coronary intervention in elderly patients with acute ST-segment elevation myocardial infarction on in-hospital, six-month, and one-year mortality. Arch Med Sci Atheroscler Dis. 2019;4:e82-e88. DOI: 10.5114/amsad.2019.85378</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lang R.M., Badano L.P., Mor-Avi V., Afilalo J., Armstrong A., Ernande L., Flachskampf F.A., Foster E. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015;16(3):233-270. DOI: 10.1093/ehjci/jev014</mixed-citation><mixed-citation xml:lang="en">Lang R.M., Badano L.P., Mor-Avi V., Afilalo J., Armstrong A., Ernande L., Flachskampf F.A., Foster E. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015;16(3):233-270. DOI: 10.1093/ehjci/jev014</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Morisky D.E., Green L.W., Levine D.M. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74. DOI: 10.1097/00005650-198601000-00007</mixed-citation><mixed-citation xml:lang="en">Morisky D.E., Green L.W., Levine D.M. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74. DOI: 10.1097/00005650-198601000-00007</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Puzin S.N.,. Grashchenkova A.N., Bogova O.T., Achkasov E.E. Rehabilitation of patients after myocardial infarction at the third stage of recovery. Annals of Anatomy. 2020;230(S):18-19. DOI: 10.1016/j.aanat.2020.151532</mixed-citation><mixed-citation xml:lang="en">Puzin S.N.,. Grashchenkova A.N., Bogova O.T., Achkasov E.E. Rehabilitation of patients after myocardial infarction at the third stage of recovery. Annals of Anatomy. 2020;230(S):18-19. DOI: 10.1016/j.aanat.2020.151532</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Rathore S.S., Weinfurt K.P., Foody J.M., Krumholz H.M. Performance of the Thrombolysis in Myocardial Infarction (TIMI) ST-elevation myocardial infarction risk score in a national cohort of elderly patients. Am Heart J. 2005;150(3):402-410. DOI: 10.1016/j.ahj.2005.03.069</mixed-citation><mixed-citation xml:lang="en">Rathore S.S., Weinfurt K.P., Foody J.M., Krumholz H.M. Performance of the Thrombolysis in Myocardial Infarction (TIMI) ST-elevation myocardial infarction risk score in a national cohort of elderly patients. Am Heart J. 2005;150(3):402-410. DOI: 10.1016/j.ahj.2005.03.069</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Sui Y.G., Teng S.Y., Qian J., Wu Y., Dou K.F., Tang Y.D., Qiao S.B., Wu Y.J. Invasive versus conservative strategy in consecutive patients aged 80 years or older with non-ST-segment elevation myocardial infarction: a retrospective study in China. J Geriatr Cardiol. 2019;16(10):741-748. DOI: 10.11909/j.issn.1671-5411.2019.10.006</mixed-citation><mixed-citation xml:lang="en">Sui Y.G., Teng S.Y., Qian J., Wu Y., Dou K.F., Tang Y.D., Qiao S.B., Wu Y.J. Invasive versus conservative strategy in consecutive patients aged 80 years or older with non-ST-segment elevation myocardial infarction: a retrospective study in China. J Geriatr Cardiol. 2019;16(10):741-748. DOI: 10.11909/j.issn.1671-5411.2019.10.006</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sutton M.G., Sharpe N. Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation. 2000;101(25):2981-2988. DOI: 10.1161/01.cir.101.25.2981</mixed-citation><mixed-citation xml:lang="en">Sutton M.G., Sharpe N. Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation. 2000;101(25):2981-2988. DOI: 10.1161/01.cir.101.25.2981</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Tao Y.J., Xia Z.L., Gao Y.J., Gao C.J. Analysis of biomarkers for predicting left ventricular remodeling after successful revascularization of acute myocardial infarction. Journal of Shanghai Jiaotong University (Medical Science). 2019;39(1):60-64. DOI: 10.3969/j.issn.1674-8115.2019.01.011</mixed-citation><mixed-citation xml:lang="en">Tao Y.J., Xia Z.L., Gao Y.J., Gao C.J. Analysis of biomarkers for predicting left ventricular remodeling after successful revascularization of acute myocardial infarction. Journal of Shanghai Jiaotong University (Medical Science). 2019;39(1):60-64. DOI: 10.3969/j.issn.1674-8115.2019.01.011</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Wojtkowska I., Stępińska J., Stępień-Wojno M., Sobota M., Kopaczewski J., Reszka Z., Kurzelewski M., Medina J. Current patterns of antithrombotic and revascularisation therapy in patients hospitalised for acute coronary syndromes. Data from the Polish subset of the EPICOR study. Kardiol Pol. 2017;75(5): 445-452. DOI: 10.5603/KP.a2017.0034</mixed-citation><mixed-citation xml:lang="en">Wojtkowska I., Stępińska J., Stępień-Wojno M., Sobota M., Kopaczewski J., Reszka Z., Kurzelewski M., Medina J. Current patterns of antithrombotic and revascularisation therapy in patients hospitalised for acute coronary syndromes. Data from the Polish subset of the EPICOR study. Kardiol Pol. 2017;75(5): 445-452. DOI: 10.5603/KP.a2017.0034</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Yoshiyama M., Kamimori K., Shimada Y., Omura T., Kino N., Iida H., Yoshikawa J. Left ventricular remodeling after myocardial infarction in antecedent hypertensive patients. Hypertens Res. 2005;28(4):293-299. DOI: 10.1291/hypres.28.293</mixed-citation><mixed-citation xml:lang="en">Yoshiyama M., Kamimori K., Shimada Y., Omura T., Kino N., Iida H., Yoshikawa J. Left ventricular remodeling after myocardial infarction in antecedent hypertensive patients. Hypertens Res. 2005;28(4):293-299. DOI: 10.1291/hypres.28.293</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Yudi M.B., Jones N., Fernando D., Clark D.J., Ramchand J., Jones E., Dakis R., Johnson D. et al. Management of Patients Aged ≥85 Years With ST-Elevation Myocardial Infarction. Am J Cardiol. 2016;118(1):44-48. DOI: 10.1016/j.amjcard.2016.04.010</mixed-citation><mixed-citation xml:lang="en">Yudi M.B., Jones N., Fernando D., Clark D.J., Ramchand J., Jones E., Dakis R., Johnson D. et al. Management of Patients Aged ≥85 Years With ST-Elevation Myocardial Infarction. Am J Cardiol. 2016;118(1):44-48. DOI: 10.1016/j.amjcard.2016.04.010</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao W, Zhao J, Rong J. Pharmacological Modulation of Cardiac Remodeling after Myocardial Infarction. Oxid Med Cell Longev. 2020;2020:8815349. DOI: 10.1155/2020/8815349</mixed-citation><mixed-citation xml:lang="en">Zhao W, Zhao J, Rong J. Pharmacological Modulation of Cardiac Remodeling after Myocardial Infarction. Oxid Med Cell Longev. 2020;2020:8815349. DOI: 10.1155/2020/8815349</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
