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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kurskvest</journal-id><journal-title-group><journal-title xml:lang="ru">Человек и его здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Humans and their health</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5746</issn><issn pub-type="epub">1998-5754</issn><publisher><publisher-name>Kursk State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21626/vestnik/2025-3/06</article-id><article-id custom-type="edn" pub-id-type="custom">QBAZHJ</article-id><article-id custom-type="elpub" pub-id-type="custom">kurskvest-1467</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICOBIOLOGICAL SCIENCES</subject></subj-group></article-categories><title-group><article-title>Заболеваемость матери и ее антропометрические параметры как предикторы массы новорожденных: региональный аспект</article-title><trans-title-group xml:lang="en"><trans-title>Maternal morbidity and anthropometric parameters as predictors of newborn weight: a regional perspective</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5641-0269</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иутинский</surname><given-names>Эдуард Михайлович</given-names></name><name name-style="western" xml:lang="en"><surname>Iutinsky</surname><given-names>Eduard M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент, доцент кафедры акушерства и гинекологии, Кировский ГМУ, г. Киров</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor, Associate Professor at the Department of Obstetrics and Gynecology, Kirov SMU, Kirov, Russian Federation</p></bio><email xlink:type="simple">iutinskiy@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8195-0996</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Железнов</surname><given-names>Лев Михайлович</given-names></name><name name-style="western" xml:lang="en"><surname>Zheleznov</surname><given-names>Lev M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, ректор, Кировский ГМУ, г. Киров</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Rector, Kirov SMU, Kirov, Russian Federation</p></bio><email xlink:type="simple">rector@kirovgma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5632-0447</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дворянский</surname><given-names>Сергей Афанасьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Dvoryansky</surname><given-names>Sergey A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, зав. кафедрой акушерства и гинекологии, Кировский ГМУ, г. Киров</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology, Kirov SMU, Kirov, Russian Federation</p></bio><email xlink:type="simple">kf1@kirovgma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кировский государственный медицинский университет (Кировский ГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kirov State Medical University (Kirov SMU)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2025</year></pub-date><volume>28</volume><issue>3</issue><fpage>50</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иутинский Э.М., Железнов Л.М., Дворянский С.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иутинский Э.М., Железнов Л.М., Дворянский С.А.</copyright-holder><copyright-holder xml:lang="en">Iutinsky E.M., Zheleznov L.M., Dvoryansky S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.kursk-vestnik.ru/jour/article/view/1467">https://www.kursk-vestnik.ru/jour/article/view/1467</self-uri><abstract><p>Цель - изучить совместное влияние перенесенных заболеваний матери во время беременности и ее антропометрических показателей (ИМТ) до зачатия на массу тела новорожденного в региональном аспекте.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено ретроспективное одноцентровое обсервационное исследование данных 5477 беременных женщин, наблюдавшихся в Кировском областном клиническом перинатальном центре в 2016-2022 гг. Выделены две основные группы: женщины с заболеваниями (n=1243) и без заболеваний (n=4234). Дополнительно все участницы были распределены по уровням ИМТ (ниже нормы, нормальный, повышенный). Исключались случаи многоплодной беременности, ожирения (ИМТ ≥30 кг/м²) и неполноты данных. Для анализа использовали описательную статистику, ANOVA, множественную линейную и логистическую регрессию.</p></sec><sec><title>Результаты</title><p>Результаты. Установлено, что заболевания матери (гипертоническая болезнь, преэклампсия, сахарный диабет, инфекция SARS-CoV-2 и фетоплацентарная недостаточность) статистически значимо снижали массу новорожденного (p&lt;0,001). Низкий ИМТ (&lt;18,5 кг/м²) усиливал негативное влияние заболеваний, увеличивая риск рождения детей с гипотрофией. При повышенном ИМТ (25,0-29,9 кг/м²) масса новорожденных возрастала на 8-10%, частично компенсируя отрицательные эффекты заболеваний.</p></sec><sec><title>Заключение</title><p>Заключение. Перенесенные заболевания и ИМТ матери являются важными факторами, определяющими массу тела новорожденного. Выявленная взаимосвязь подчеркивает значимость персонализированного подхода к ведению беременности, включая контроль за здоровьем и оптимизацию антропометрических показателей матери для снижения рисков гипотрофии и улучшения перинатальных исходов.</p></sec></abstract><trans-abstract xml:lang="en"><p>Objective - to investigate the combined influence of maternal diseases during pregnancy and preconception anthropometric parameters (BMI) on the weight of newborns from a regional perspective.</p><sec><title>Materials and methods</title><p>Materials and methods. A retrospective single-center observational study was conducted using data from 5477 pregnant women monitored at the Kirov Regional Clinical Perinatal Center between 2016 and 2022. Two main groups were identified: women with diseases (n = 1243) and women without diseases (n = 4234). Additionally, participants were stratified based on BMI levels (below normal, normal, elevated). Cases involving multiple pregnancies, obesity (BMI ≥ 30 kg/m²), and incomplete data were excluded. The statistical analysis included descriptive statistics, ANOVA, multiple linear regression, and logistic regression.</p></sec><sec><title>Results</title><p>Results. The study demonstrated that maternal diseases-including hypertensive disease, preeclampsia, diabetes mellitus, SARS-CoV-2 infection, and fetoplacental insufficiency-significantly reduced the weight of the newborn (p&lt;0.001). A low BMI (&lt; 18.5 kg/m²) intensified the negative effects of these diseases, thereby increasing the risk of delivering infants with hypotrophy. Conversely, an elevated BMI (25.0-29.9 kg/m²) was associated with an 8-10% increase in newborn weight, partially counterbalancing the adverse influence of maternal diseases.</p></sec><sec><title>Conclusion</title><p>Conclusion. Maternal diseases and BMI are crucial factors determining newborn weight. The identified association underscores the importance of a personalized approach to pregnancy management, including meticulous health monitoring and the optimization of maternal anthropometric parameters to reduce the risk of hypotrophy and enhance perinatal outcomes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>масса новорожденного</kwd><kwd>ИМТ матери</kwd><kwd>заболевания при беременности</kwd><kwd>гипотрофия плода</kwd><kwd>ретроспективное исследование</kwd><kwd>перинатальные исходы</kwd><kwd>персонализированный подход</kwd></kwd-group><kwd-group xml:lang="en"><kwd>newborn weight</kwd><kwd>maternal BMI</kwd><kwd>pregnancy-related diseases</kwd><kwd>fetal hypotrophy</kwd><kwd>retrospective study</kwd><kwd>perinatal outcomes</kwd><kwd>personalized approach</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Scifres C.M. 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