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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kurskvest</journal-id><journal-title-group><journal-title xml:lang="ru">Человек и его здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Humans and their health</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5746</issn><issn pub-type="epub">1998-5754</issn><publisher><publisher-name>Kursk State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21626/vestnik/2025-3/03</article-id><article-id custom-type="edn" pub-id-type="custom">LODAWF</article-id><article-id custom-type="elpub" pub-id-type="custom">kurskvest-1463</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Клинико-диагностическая характеристика ишемического инсульта у пациентов молодого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and diagnostic characteristics of ischemic stroke in young patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4058-291X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатьева</surname><given-names>Ольга Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatieva</surname><given-names>Olga I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент кафедры психиатрии, наркологии и неврологии, МГУ им. Н.П. Огарёва, г. Саранск</p></bio><bio xml:lang="en"><p>Associate Professor, Department of Psychiatry, Narcology and Neurology, МSU after N.P. Ogarev, Saransk, Russian Federation</p></bio><email xlink:type="simple">ignat-oi@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-3633-8538</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жегалина</surname><given-names>Анна Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Zhegalina</surname><given-names>Anna N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент, МГУ им. Н.П. Огарёва, г. Саранск</p></bio><bio xml:lang="en"><p>Student, МSU after N.P. Ogarev, Saransk, Russian Federation</p></bio><email xlink:type="simple">sannanikolaevna@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Мордовский государственный университет им. Н.П. Огарёва (МГУ им. Н.П. Огарёва)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mordovia State University named after N.P. Ogarev (МSU after N.P. Ogarev)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2025</year></pub-date><volume>28</volume><issue>3</issue><fpage>25</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Игнатьева О.И., Жегалина А.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Игнатьева О.И., Жегалина А.Н.</copyright-holder><copyright-holder xml:lang="en">Ignatieva O.I., Zhegalina A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.kursk-vestnik.ru/jour/article/view/1463">https://www.kursk-vestnik.ru/jour/article/view/1463</self-uri><abstract><p>Изучение особенностей ишемического инсульта у пациентов молодого возраста представляется актуальным, поскольку детальная оценка факторов риска необходима для улучшения профилактики, а сведения анамнеза, клиники, инструментальных и лабораторных данных важны для прогнозирования исходов заболевания.</p><p>Цель - анализ факторов риска, клинико-диагностических характеристик, госпитальных исходов ишемического инсульта у пациентов молодого возраста.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен ретроспективный анализ медицинских карт пациентов с ишемическим инсультом в возрасте от 18 до 45 лет. В процессе изучения клинико-диагностических характеристик ишемического инсульта учитывали пол и возраст больных, социально-экономический статус, вредные привычки и сопутствующую соматическую патологию, результаты инструментальных и лабораторных исследований, особенности распределения по подтипам, динамику неврологического дефицита по шкалам NIHSS, Ривермид, Рэнкин в зависимости от подтипа. Проведен статистический анализ полученных результатов с использованием среднего арифметического и стандартного отклонения, частоты и доли (в %), t-критерий Стьюдента.</p></sec><sec><title>Результаты</title><p>Результаты. В ходе проведенного исследования выявлены достоверные половозрастные и клинико-диагностические особенности ишемического инсульта у пациентов молодого возраста: наибольшее количество случаев отмечено среди мужчин от 35 до 45 лет, основными факторами риска стали малоподвижный образ жизни, хронический стресс, курение, артериальная гипертензия, гиперфибриногенемия и дислипидемия. Сопутствующая патология представлена имеющимися и вновь выявленными заболеваниями сердечно-сосудистой системы и сахарным диабетом. Превалировали криптогенный и лакунарный подтипы инсульта легкой степени тяжести в бассейне внутренней сонной артерии с двигательными нарушениями, с достоверно значимыми критериями благоприятного реабилитационного прогноза.</p></sec><sec><title>Заключение</title><p>Заключение. Результаты проведенного исследования подтвердили значимость мониторинга факторов риска ишемического инсульта, в первую очередь у мужчин в возрасте от 35 до 45 лет, важность своевременного выявления, лечения и профилактики сопутствующей патологии, проведения расширенного диагностического поиска.</p></sec></abstract><trans-abstract xml:lang="en"><p>The study of the characteristics of ischemic stroke in young patients seems relevant, since a detailed assessment of risk factors is necessary to improve prevention, and information on the anamnesis, clinical, instrumental and laboratory data is important for predicting disease outcomes.</p><p>Objective - to analyze risk factors, clinical and diagnostic characteristics, and hospital outcomes of ischemic stroke in young patients.</p><sec><title>Materials and methods</title><p>Materials and methods. A retrospective analysis of medical records of patients with ischemic stroke aged 18 to 45 years was performed. In the process of studying the clinical and diagnostic characteristics of ischemic stroke, the following were taken into account: gender and age of patients, socioeconomic status, bad habits and concomitant somatic pathology, results of instrumental and laboratory studies, features of distribution by subtypes, dynamics of neurological deficit according to the NIHSS, Rivermead, Rankin scales depending on the subtype. Statistical analysis of the obtained results was performed using the arithmetic mean and standard deviation, frequency and proportion (in %), Student's t-test.</p></sec><sec><title>Results</title><p>Results. The study revealed reliable age, gender, and clinical diagnostic features of ischemic stroke in young patients: the largest number of cases was observed among men aged 35 to 45 years, the main risk factors were a sedentary lifestyle, chronic stress, smoking, hypertension, hyperfibrinogenemia, and dyslipidemia. Concomitant pathology was represented by existing and newly diagnosed cardiovascular diseases and diabetes mellitus. Cryptogenic and lacunar subtypes of mild stroke in the internal carotid artery with motor impairments prevailed, with significantly significant criteria for a favorable rehabilitation prognosis.</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of the study confirmed the importance of monitoring risk factors for ischemic stroke, primarily in men aged 35 to 45 years, the importance of timely detection, treatment and prevention of concomitant pathology, and an extended diagnostic search. Key words: ischemic stroke, young patients, risk factors, concomitant diseases, pathogenetic subtypes, medical rehabilitation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемический инсульт</kwd><kwd>пациенты молодого возраста</kwd><kwd>факторы риска</kwd><kwd>сопутствующие заболевания</kwd><kwd>патогенетические подтипы</kwd><kwd>медицинская реабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic stroke</kwd><kwd>young patients</kwd><kwd>risk factors</kwd><kwd>concomitant diseases</kwd><kwd>pathogenetic subtypes</kwd><kwd>medical rehabilitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Montanaro V.V., Freitas D.D., Ruiz M.C., Cavalcanti E.B., Marinho P.B., Freitas M.C., Oliveira E.M. Ischemic stroke in young adults: Profile of SARAH Hospital Brasília from 2008 to 2012. Neurologist. 2017;22(2):61-63. 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