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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kurskvest</journal-id><journal-title-group><journal-title xml:lang="ru">Человек и его здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Humans and their health</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5746</issn><issn pub-type="epub">1998-5754</issn><publisher><publisher-name>Kursk State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21626/vestnik/2023-3/05</article-id><article-id custom-type="edn" pub-id-type="custom">ZWNOMZ</article-id><article-id custom-type="elpub" pub-id-type="custom">kurskvest-1212</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Скорость окисления крови как предиктор развития фибрилляции предсердий в послеоперационном периоде при проведении шунтирования коронарных артерий</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5362-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шерешнева</surname><given-names>Марина Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры терапии ИНПО, ЯГМУ, г. Ярославль</p></bio><email xlink:type="simple">m.shereshneva@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6278-374X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильин</surname><given-names>Михаил Витальевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, зав. кафедрой терапии им. профессора Е.Н. Дормидонтова, ЯГМУ, г. Ярославль</p></bio><email xlink:type="simple">dekanat-2011@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9961-7024</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Староверов</surname><given-names>Иван Николаевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>зав. отделением кардиохирургии, ОКБ, г. Ярославль</p></bio><email xlink:type="simple">ivstaroverov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Ярославский государственный медицинский университет (ЯГМУ)</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Областная клиническая больница (ОКБ)</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>11</month><year>2023</year></pub-date><volume>26</volume><issue>3</issue><fpage>36</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шерешнева М.В., Ильин М.В., Староверов И.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Шерешнева М.В., Ильин М.В., Староверов И.Н.</copyright-holder><copyright-holder xml:lang="en">Шерешнева М.В., Ильин М.В., Староверов И.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.kursk-vestnik.ru/jour/article/view/1212">https://www.kursk-vestnik.ru/jour/article/view/1212</self-uri><abstract><p>Развитие послеоперационной фибрилляции предсердий (ФП) связано с хирургической травмой, активацией нейтрофилов, высвобождением провоспалительных цитокинов и окислительным стрессом. Цель: оценка прогностической значимости определения скорости окисления крови в отношении риска развития фибрилляции предсердий в раннем послеоперационном периоде при проведении операции шунтирования коронарных артерий. Материал и методы. В исследование включены 68 больных стабильной ишемической болезнью сердца (ИБС), которым выполнена операция шунтирования коронарных артерий в условиях искусственного кровообращения (On-pump), параллельного искусственного кровообращения и на работающем сердце (Off-pump). Показатели индуцированного окисления крови изучались с помощью биологического кислородного монитора, определялась скорость окисления крови. Результаты. Установлено, что скорость окисления крови является значимым (p&lt;0,05) компонентом, ассоциированным с развитием фибрилляции предсердий (r=0,90) при проведении хирургической реваскуляризации миокарда. По результатам логистического регрессионного анализа установлено, что скорость окисления крови оказывает влияние на развитие фибрилляции предсердий в послеоперационном периоде коронарного шунтирования. Выводы. Показатель скорости окисления крови является предиктором развития фибрилляции предсердий при проведении шунтирования коронарных артерий вне зависимости от выбранной методики хирургического вмешательства.</p></abstract><kwd-group xml:lang="ru"><kwd>окисление крови</kwd><kwd>фибрилляция предсердий</kwd><kwd>шунтирование коронарных артерий</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Michniewicz E., Mlodawska E., Lopatowska P., Tomaszuk-Kazberuk A., Malyszko J. Patients with atrial fibrillation and coronary artery disease - Double trouble. Adv Med Sci. 2018;63(1):30-35. 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