kurskvestЧеловек и его здоровьеHumans and their health1998-57461998-5754Kursk State Medical University10.21626/vestnik/2023-1/07ZXSPTLkurskvest-1146Research ArticleМЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИMEDICOBIOLOGICAL SCIENCESОбзор литературы: фармакологические эффекты витамина D в организме для повышения спортивных результатовLiterature review: pharmacological effects of vitamin D in the body to enhance athletic performancehttps://orcid.org/0000-0002-6175-5752СаркисянНарине ГришаевнаSarkisyanNarine G.

д-р мед. наук, доцент кафедры терапевтической стоматологии и пропедевтики стоматологических заболеваний, УГМУ, г. Екатеринбург

Dr. Sci. (Med.), Associate Professor at the Department of Therapeutic dentistry and propedeutics of dental diseases, USMU, Yekaterinburg, Russian Federation

narine_25@mail.ruhttps://orcid.org/0000-0003-1223-5790ГайсинаЕлена ФахаргалеевнаGaisinaElena F.

канд. мед. наук, доцент кафедры фармакологии и клинической фармакологии, УГМУ, г. Екатеринбург

Cand. Sci. (Med.), Associate Professor at the Department of Therapeutic dentistry and propedeutics of dental diseases, USMU, Yekaterinburg, Russian Federation

egaisina68@mail.ruhttps://orcid.org/0000-0001-9208-9417ДобринскаяМария НиколаевнаDobrinskayaMariya N.

канд. мед. наук, доцент кафедры фармакологии и клинической фармакологии, УГМУ, г. Екатеринбург.

Cand. Sci. (Med.), Associate Professor at the Department of Pharmacology and clinical pharmacology, USMU, Yekaterinburg, Russian Federation

maria-nd@mail.ruШмаковаМилана АлексеевнаShmakovaMilana A.

студент, УГМУ, г. Екатеринбург

student, USMU, Yekaterinburg, Russian Federation

milana.shmakova@yandex.ruАстрюхинаПолина ИгоревнаAstryukhinaPolina I.

студент, УГМУ, г. Екатеринбург

student, USMU, Yekaterinburg, Russian Federation

astryukhina_polina@mail.ruГоськовАртём СергеевичGoskovArtyom S.

магистрант Института физической культуры и молодежной политики, УрФУ, г. Екатеринбург

Master's student at the Institute of Physical Culture and Youth Policy, UrFU, Yekaterinburg, Russian Federation

gasya1996@list.ruУральский государственный медицинский университет (УГМУ)РоссияUral State Medical University (USMU)Russian FederationУральский федеральный университет (УрФУ)РоссияUral Federal University (UrFU)Russian Federation2023220520232615363Copyright © Саркисян Н.Г., Гайсина Е.Ф., Добринская М.Н., Шмакова М.А., Астрюхина П.И., Госьков А.С., 20232023Саркисян Н.Г., Гайсина Е.Ф., Добринская М.Н., Шмакова М.А., Астрюхина П.И., Госьков А.С.Sarkisyan N.G., Gaisina E.F., Dobrinskaya M.N., Shmakova M.A., Astryukhina P.I., Goskov A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.kursk-vestnik.ru/jour/article/view/1146

Проанализированы исследования (отечественные и зарубежные) о влиянии витамина D на мышечную силу, скорость восстановления мышц, максимальное потребление кислорода и профилактику снижения травм скелетных мышц. Одновременно выяснено, что спортсмены подвержены гиповитаминозам не реже, чем стандартные группы населения вследствие более высоких физических нагрузок. Однозначно можно сказать, что при дефицитных состояниях прием витамина D улучшает физическую форму спортсменов и может скорректировать их состояние в осенне-весенний период. Целью данного обзора является анализ литературных данных о значении фармакологических эффектов витамина D в работе опорно-двигательной системы организма и роли в повышении спортивных результатов. Материалы и методы. Основным источником информации была выбрана электронная научная библиотека Pubmed/MEDLINE. Дополнительно поиск охватил репозитории препринтов открытого доступа eLIBRARY.RU за 2016-2022 гг. Ключевыми словами для поискового запроса являлись «витамин D», «кальцитриол», «спорт», «атлеты».Результаты исследования освещены с учетом рекомендаций PRISMA. Результаты. Длительность и качество инсоляции непосредственно влияют на количество витамина D. Дополнительная солнечная экспозиция в комплексе с употреблением препаратов витамина D способствует устранению его дефицита. Дефицит витамина D может привести к уменьшению концентрации внутриядерного VDR и снижению экспрессии генов VDR , что способствует развитию миопатии, вследствие атрофии мышечных волокон типа IIA. Оправдано дополнительное обогащение специальных растворов электролитов водорастворимым витамином D. Заключение. Постоянный контроль концентрации 25(OH)D в сыворотке крови спортсменов является неотъемлемой составляющей в разработке рекомендаций для улучшения здоровья и спортивных результатов в тренировочном и соревновательном режимах.

Studies (domestic and foreign) on the effect of vitamin D on muscle strength, muscle recovery rate, maximum oxygen consumption and prevention of skeletal muscle injury reduction have been analyzed. At the same time it was found that athletes are susceptible to hypovitaminosis no less often than standard population groups due to higher physical loads. It is unequivocally possible to say that vitamin D supplementation improves the physical fitness of athletes and can correct their condition in the autumn-spring period. Objective: an analysis of literature data based on the significance of the pharmacological effects of vitamin D in the functioning of the musculoskeletal system of the body and its role of improving athletic performance. Material and methods. The Pubmed/MEDLINE digital scientific library was chosen as the main source of information. Additionally, the search included the repositories of open access preprints from eLIBRARY.RU for 2016-2022. Key words for the search query were "vitamin D," "calcitriol," "sports," and "athletes." The results of the study are reported taking into account PRISMA recommendations. Results. Duration and quality of insolation directly affect vitamin D levels. Additional sun exposure combined with the use of vitamin D preparations contributes to the elimination of vitamin D deficiency. Vitamin D deficiency can lead to decreased intranuclear VDR concentrations and decreased VDR gene expression, which contributes to myopathy following atrophy of type IIA muscle fibers. Additional enrichment of special electrolyte solutions with water-soluble vitamin D is reasonable. Conclusion. Continuous monitoring of the concentration of 25(OH)D in the blood serum of athletes is an integral part in the development of recommendations for improving health and sports performance in training and competitive regimes. Individual correction of vitamin D should be carried out in accordance with changes in its level in each athlete.

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The authors declare that there are no conflicts of interest present.