Founded in 1998

№1 - 2010 Year

CLINICAL MEDICINE

      The comparative estimate of the efficiency of three schemes of preparation to labor with using of Mifepristone was conducted. 32 patients (from the І group) were appointed the mifepristone 200 mg per day during 2 days. In the ІІ group (n = 32) before using the mifepristone the sibazonum 2 ml (10 mg) and nospan 4 ml (80 mg) in 400 ml 5% glucosa solution were intravenously introducted during 3 days. In the ІІІ group (n = 32) 20 ml natrii oxibutirati solution 20% was intravenouslyprescribed during 3 days and the Mifepristone was appointed. The efficiency of the preparation was the highest in the ІІ and ІІІ groups, "mature" cervix uteri was observed in 87.5% and 84.4% of women. The appointment of Mifepristone was unefficiently in 43.8% of patients in the І group with "immature" cervix uteri and the supplementary curing of prostaglandinum was necessary. And in the І group 12.5% causes the hyperstimulation of uteri was observed.

Key words: Mifepristone, preparation of cervix to labor, labor, hyperstimulation of uteri

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