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Quarterly review journal          Contents ¹1 - 2010 year

KURSKIY SCIENTIFICALLY-PRACTICAL HERALD

"PERSONS AND HIS HEALTH"

Scientifically-practical journal from Kursk state medical university, Central-Chernozemnogo scientific centre to Russian Academy of the Medical Sciences, Kursk regional branch of the Russian Academy of Natural Sciences

Founded in 1998

¹1 - 2010 Year


CLINICAL MEDICINE


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Characteristics of immune and oxidant disorders in patients with diffuse fibro-purulent peritonitis


© Blinkov Yu.Yu., Sukovatykh B.S., Stroev Yu.S., Konoplya A.I.

General Surgery Department of the Kursk State Medical University, Kursk
E-mail: blinkov_you@mail.ru


      At the moment of admission to the hospital patients with diffuse peritonitis are found to have significant disorders of cellular and humoral immunity, complement system, functional-metabolic activity of neutrophiles, cytokine balance, processes of lipid peroxidation and anti-oxidant protection, which are getting worse in the first 24 hours after operation. The standard pharmacotherapy provided in postoperative period in this group of patients partially improves the changed indicators of immune and oxidant status that is correlating with the development of inflammatory complications.

Key words: diffuse peritonitis, immunity, lipid peroxidation, anti-oxidant status

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