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KURSKIY SCIENTIFICALLY-PRACTICAL HERALD"PERSONS AND HIS HEALTH"Scientifically-practical journal from Kursk state medical university, Central-Chernozemnogo scientific centre to Russian Academy of the Medical Sciences, Kursk regional branch of the Russian Academy of Natural SciencesFounded in 1998 ¹1 - 2010 YearCLINICAL MEDICINEFull Russian article : Evaluation of the neurohormonal system in patients with chronic heart failure characterized by postinfarction cardiosclerosis© Pribylova N.N., Osipova O.A., Konovalova L.V. Department of Internal Diseases of the Postgraduate Education Faculty of the Kursk State Medical University, Kursk; Department of Internal Diseases N 1 of the Medical Faculty of the Belgorod State University, Belgorod; St. Ioasaf Belgorod Regional Clinical Hospital, Belgorod A total investigation of 115 patients. Chronic heart failure (CHF) of the 1-st functional class (FC) was found in 19 patients (16.5%), 2-nd FC in 48 patients (41.8%), 3-d FC in 40 (34.7%) and 4-th FC in 8 (6.9%). In their peripheral venous blood plasma norepinephrine, aldosterone and brain natriuretic peptide were investigated. The amount of N in patients with cardiosclerosis post infarction increased in the 2-d, 3-d and 4-th FC; A increased in all the groups and with normal (FV) and didn’t depend on diastolic or systolic kind of CHF. The amount of BNP also increased with the appearance of systolic heart insufficiency and grew as the level of CHF increased . The BNP level can be a diagnostic test for a low FC's grade of CHF. Key words: chronic heart failure (ÑÍF), norepinephrine, aldosterone, brain natriuretic peptide * For viewing of the full Russian version of article it is necessary Adobe Reader |
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